The Department will continue to assess states’ compliance with obligations and commitments, including the publication of a congressionally mandated Compliance Report detailing noncompliant activity annually. We will continue to lead multilateral efforts that urge noncompliant states to return to compliance with their obligations and to understand the challenges associated with future nuclear disarmament verification, in particular, through the International Partnership for Nuclear Disarmament Verification. We will work with the Congress and our European allies to fix the flaws in the Joint Comprehensive Plan of Action and continue to hold Iran strictly accountable to its agreed-upon commitments. Cross-Agency Collaboration The Department of State’s own nonproliferation security assistance programs work to reinforce diplomatic engagement to counter WMD proliferation. The Department and USAID also work with the Department of Defense’s Office of Cooperative Threat Reduction, the Department of Energy (DOE), especially the National Nuclear Security Administration (NNSA) and the National Laboratories, the Department of Homeland Security Container Security Initiative and other programs, the Department of Justice (DOJ), the Department of Treasury (DOT), and the Department of Commerce (DOC). Risk The United States relies on many international and multilateral organizations to help achieve our nonproliferation objectives. Because many of these organizations work by consensus, one state can refuse or delay prompt action or achievement of our immediate and longer-term nonproliferation objectives. New technologies are being developed and practical applications for them are being devised at an astonishing pace. Lines are being blurred between chemical and biological agents; new organisms are being developed; there is worldwide access to dual-use life science research; and the internet provides instructions on the production of chemical and biological weapons. The Department keeps abreast of technological change; engages with partner countries to update the control lists of the multilateral export control regimes; and is working to create new frameworks and norms to assess the benefits and risks of dual-use research in the life sciences.  

Terrorism and Global Safety 

: Defeat ISIS, al-Qa’ida and other transnational terrorist organizations, and counter state-sponsored, regional, and local terrorist groups that threaten U.S. national security interests